PV Bulletin

Increased risk of wear and corrosion identified with certain cobalt chrome modular neck hip replacements

MHRA warns NHS trusts to conduct clinical reviews for patients with specific cobalt-chrome hip replacements due to wear and corrosion risks.

Primary source: Profemur Cobalt Chrome Modular Neck Hip Replacements: Higher than anticipated risk of revision surgery, metal-wear effec

PV Impact Brief

Urgency: HighConfidence: high

What changed

NHS trusts and hospitals are advised to identify patients with specific cobalt-chrome modular neck components and invite them for clinical reviews to discuss potential risks.

Why it matters

This revision is crucial as complications such as tissue reactions from wear can necessitate revision surgeries, affecting patient safety and healthcare outcomes.

Action needed

Healthcare providers must implement a follow-up process for patients with identified cobalt-chrome modular neck components, monitoring for new or unexpected symptoms including pain, stiffness, or instability.

Relevant for
Medical Safety Lead
Processes impacted
Signal Management
Owner

Regulatory Intelligence Lead

Review cadence

Regular updates as new safety data emerges.

Evidence and confidence

Confidence: highSource updated: Aug 26, 2026

Full briefing

Practical implication

Healthcare providers must implement a follow-up process for patients with identified cobalt-chrome modular neck components, monitoring for new or unexpected symptoms including pain, stiffness, or instability.

The Medicines and Healthcare products Regulatory Agency (MHRA) has identified an increased risk of wear and corrosion in cobalt-chrome modular neck hip replacements. As a precaution, NHS trusts are instructed to notify and invite approximately 750 patients with these devices for clinical reviews.

What changed: NHS trusts and hospitals are advised to identify patients with specific cobalt-chrome modular neck components and invite them for clinical reviews to discuss potential risks.

Why it matters: This revision is crucial as complications such as tissue reactions from wear can necessitate revision surgeries, affecting patient safety and healthcare outcomes.

Practical implication: Healthcare providers must implement a follow-up process for patients with identified cobalt-chrome modular neck components, monitoring for new or unexpected symptoms including pain, stiffness, or instability.

View original source

  • Source: MHRA - News and communications
  • Published at source: 2026-08-26T00:00:00.000Z
  • Discovered by monitor: 2026-08-26T23:35:59.462Z

Published from the regulator source ingestion pipeline after PV impact triage.

#Safety Signal#Safety Signals#Source-ingestion#Regulator-monitor#Uk#Gov.uk

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